Presentation
Since 1998, Nadège Bondurand has investigated the molecular and cellular bases of neural crest development and associated disorders by combining expertise in genetics, molecular and developmental biology. To this end, she engineered several cellular and mice models and used adequate patient cohorts. She particularly focused on the role of SOX10 and EDN3/EDNRB during enteric nervous system development. Recently, Nadège Bondurand characterized the role of A-to-I RNA editing in neural crest development in mice.
http://cvscience.aviesan.fr/cv/1561/nadege-bondurand
Resources & publications
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Journal (source)Gastroenterology
Differentiation of Mouse Enteric Nervous System Progenitor Cells Is Controlle...
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Journal (source)Dev. Biol.
Mouse models of Hirschsprung disease and other developmental disorders of the...
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Journal (source)Hum. Mol. Genet.
Subnuclear re-localization of SOX10 and p54NRB correlates with a unique neuro...
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Journal (source)Stem Cell Res
Generation of an iPSC line (IMAGINi022-A) from a patient carrying a SOX10 mis...
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Journal (source)Nat Commun
ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cel...
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Journal (source)J Clin Invest
Dysregulation of the NRG1/ERBB pathway causes a developmental disorder with g...